CD105 (ENG) Mouse Monoclonal Antibody [Clone ID: SN6]

CAT#: SM1177R

CD105 (ENG) mouse monoclonal antibody, clone SN6, PE

Product Images

Staining of KG1 cells with Mouse anti Human CD105 PE (SM1177R/RT).

Specifications

Product Data

• Clone Name: SN6
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl.
• Reactivities: Equine, Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Partially purified cell membrane antigens from fresh leukaemia cells
• Specificity: This antibody recognises the human CD105 cell surface antigen, a glycoprotein homodimer of 95 kD subunits.
• Formulation: PBS, pH 7.4, containing 0.09% sodium azide as preservative and 1% BSA as stabilizer.
  Label: PE
  State: Lyophilized purified IgG fraction.
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Restore with 1.0 ml distilled water.
• Purification: Affinity Chromatography on Protein G.
• Conjugation: PE
• Storage: Prior to and following reconstitution store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
  This Product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: endoglin
• Database Link:
  Entrez Gene 2022 Human
  UniProt ID P17813
• Background: CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
• Synonyms: ENG, END, HHT1, ORW, ORW1