CD32A (FCGR2A) Mouse Monoclonal Antibody [Clone ID: AT10]

CAT#: SM1092B

CD32A (FCGR2A) mouse monoclonal antibody, clone AT10, Biotin

Product Images

Staining of human peripheral blood monocytes with Mouse anti Human CD32-Biotin.

Specifications

Product Data

• Clone Name: AT10
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of neat antibody to label 10⁶ cells or 100 µl whole blood.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: K562 cell line. Spleen cells from immunised BALB/c mice were fused with cells of the NS1 myeloma cell line.
• Specificity: This antibody recognizes the CD32 antigen.
  Clone AT10 blocks the binding of IgG to Fc gamma R11. SM1092LE is recommended for this purpose.
• Formulation: PBS, pH 7.4
  Label: Biotin
  State: Liquid purified IgG fraction.
  Stabilizer: 1% BSA
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Biotin
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Fc fragment of IgG receptor IIa
• Database Link:
  Entrez Gene 2212 Human
  UniProt ID P12318
• Background: CD32 is a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets.
• Synonyms: Fc-gamma RII-a, Fc-gamma-RIIa, CDw32, FCGR2A, FCG2, FCGR2A1, IGFR2