CD11a (ITGAL) Mouse Monoclonal Antibody [Clone ID: 38]

CAT#: SM1080A

CD11a (ITGAL) mouse monoclonal antibody, clone 38, Azide Free

Product Images

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD11a:AZIDE FREE

Specifications

Product Data

• Clone Name: 38
• Applications: FC, FN, IHC, IP
• Recommended Dilution: Flow cytometry: 1/50 - 1/100; use 5 µl of the suggested working dilution to label 10e6 cells in 100µl.
  Functional Assays.
  Immunoprecipitation.
  Immunohistochemistry on frozen sections.
  Recommended positive control tissue: Human Tonsil.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Specificity: This antibody recognises the integrin alphaL subunit, a 180kD glycoprotein expressed by all human leucocytes. The molecule is involved in cell-cell adhesion processes and binds to ICAM-1, 2 and 3. This antibody neutralises CD11a mediated adhesion.
• Formulation: State: Azide Free
  State: Liquid purified IgG
• Concentration: lot specific
• Purification: Affinity chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: integrin subunit alpha L
• Database Link:
  Entrez Gene 3683 Human
  UniProt ID P20701
• Background: CD11a is a member of the integrin family of cell adhesion molecules. It is a glycoprotein expressed in combination with the CD18 beta chain. The complex is a member of the beta 2 integrin family. These molecules function in cell adhesion and specifically bind to CD54, ICAM2, ICAM3. CD11a is expressed on thymocytes, T and B lymphocytes, granulocytes, monocytes, and macrophages.
• Synonyms: Integrin alpha-L, LFA1, LFA-1