CD11a / ITGAL Rat Monoclonal Antibody [Clone ID: I21/7]

CAT#: SM013PT

CD11a / ITGAL rat monoclonal antibody, clone I21/7, Purified

Specifications

Product Data

• Clone Name: I21/7
• Applications: FC, IP
• Recommended Dilution: Flow Cytometry.
  Immunoprecipitation.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Whole BW5147 cells.
• Specificity: This antibody recognises CD11a.
  Clone I21/7 is reported to block the cytolytic activity of cytotoxic T cell lines). We recommend the use of SM013LE for this purpose.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  UniProt ID P24063
• Background: CD11a is a 170 - 180kD type I membrane glycoprotein, which is also known as the integrin alphaL subunit. CD11a is a member of the intergrin family of adhesion molecules. The CD11a molecule is expressed on all leucocytes and associates with CD18 to form a heterodimer at the cell surface. The CD11a/CD18 heterodimer binds to intercellular adhesion molecules (ICAM); ICAM-1, ICAM-2 and ICAM-3 and is involved in cell-cell adhesion processes.
• Synonyms: Integrin alpha-L, LFA1, LFA-1