alpha 1 Antichymotrypsin (SERPINA3) Rabbit Polyclonal Antibody

CAT#: DP047-05

alpha 1 Antichymotrypsin (SERPINA3) rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on frozen sections.
  Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1:25-1:50 in an ABC method (30 minutes at room temperature).
  Recommended Positive Control: Tonsil.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Alpha-1-antichymotrypsin isolated from human serum
• Specificity: The antibody is specific against human alpha-1-antichymotrypsin.
  Cellular Localization: Cytoplasmic.
• Formulation: Containing sodium azide as preservative
  State: Purified
  State: Liquid Ig fraction
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: serpin family A member 3
• Database Link:
  Entrez Gene 12 Human
  UniProt ID P01011
• Background: Alpha 1 Antichymotrypsin is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variation in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
• Synonyms: SERPINA3, AACT, GIG24, GIG25
• Note: This antibody shows cross reactivity against wide range of mammalian species.