TGF beta 1 (TGFB1) Mouse Monoclonal Antibody [Clone ID: 2E6]

CAT#: DM1046

TGF beta 1 (TGFB1) mouse monoclonal antibody, clone 2E6, Azide Free

Specifications

Product Data

• Clone Name: 2E6
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot: This antibody, used at a concentration of 1-10 ng/ml, will allow visualization of 100 ng/lane of TFG-beta.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: TGF-β from human platelets
• Specificity: Western blotting demonstrated that this antibody reacts with the dimeric (25 kDa) and monomeric (12.5 kDa.) forms of TGF-beta under both non-reducing and reducing conditions respectively. This antibody recognizes both human platelet-derived and recombinant TGF-beta in ELISA.
• Formulation: 0.01M PBS, pH 7.0
  State: Azide Free
  State: Lyophilized purified IgG
• Reconstitution Method: Restore with double distillated water is recommended to adjust the final concentration to 1.00 mg/ml
• Purification: Protein G affinity purified
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: transforming growth factor beta 1
• Database Link:
  Entrez Gene 7040 Human
  UniProt ID P01137
• Background: TGF beta 1 (Transforming Growth Factor Beta 1) is a multifunctional peptide capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed as well as non neoplastic tissues, release transforming growth factors; and essentially all cells possess a specific TGF beta 1 receptor. The multimodal nature of TGF beta 1 is seen in its ability to stimulate or inhibit cellular proliferation. TGF beta 1 plays a fundamental role in tissue growth and differentiation involvement in adipogenesis, myogenesis, chondrogenesis, osteogenesis, epithelial cell differentiation and immune cell function.
  The C-terminal 112 amino acids constitute the mature protein.
• Synonyms: TGFB, Transforming growth factor beta-1, TGF-beta-1