Glycophorin A (GYPA) Mouse Monoclonal Antibody [Clone ID: JC159]

CAT#: DM066

Glycophorin A (GYPA) mouse monoclonal antibody, clone JC159, Supernatant

Product Images

Formalin fixed paraffin embedded human tonsils stained with glycophorin A monoclonal antibody (Cat.#DM066).

Specifications

Product Data

• Clone Name: JC159
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on formalin fixed paraffin embedded sections: use a dilution of 1:25-1:50 in an ABC method (30 minutes at room temperature).
  Recommended positive control: Tonsil
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Formalin fixed membrane from a Hairy cell leukemia
• Specificity: This antibody reacts with glycophorin A in the erythroid cells. It can stain erythroid cells at all stages of development and differentiation. The antibody may be useful in the identification of neoplastic erythroblasts.
  Cellular Localization: Cell membrane
• Formulation: State: Supernatant
  State: Ttissue Culture Supernatant
  Preservative: Less than 0.1% Sodium Azide
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: glycophorin A (MNS blood group)
• Database Link:
  Entrez Gene 2993 Human
  UniProt ID P02724
• Background: Glycophorins A (GPA) and B (GPB) are single pass membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors and also binds influenza virus.
• Synonyms: Glycophorin-A, GPA, PAS-2, Sialoglycoprotein alpha, MN sialoglycoprotein