IL17 (IL17A) Mouse Monoclonal Antibody [Clone ID: OTI2D6F4]

CAT#: CF814526

Carrier-free (BSA/glycerol-free) IL-17A mouse monoclonal antibody, clone OTI2D6F4

Specifications

Product Data

• Clone Name: OTI12H7 OTI13B1 OTI13E7 OTI13F3 OTI1C10 OTI1E4 OTI1G6 OTI1G8 OTI2B7 OTI2D6C2 OTI2D6F4 OTI3D5 OTI3F6 OTI3H2 OTI3H3 OTI4A12 OTI4B1 OTI4E1 OTI7E6 OTI7H6 OTI7H7 OTI8F4 OTI9C2 OTI9C4 OTI9D4 OTI9G1 OTI9G5
• Applications: ELISA
• Recommended Dilution: ELISA 1:5000-10000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human IL-17A (NP_002181) produced in 293 cell.
• Formulation: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Predicted Protein Size: 17.5 kDa
• Gene Name: interleukin 17A
• Database Link:
  NP_002181
  Entrez Gene 3605 Human
  UniProt ID Q16552
• Background: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
• Synonyms: CTLA-8; CTLA8; IL-17; IL-17A; IL17; ILA17

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction