Glutamine Synthetase (GLUL) Mouse Monoclonal Antibody [Clone ID: OTI2C12]
CAT#: CF814202
Carrier-free (BSA/glycerol-free) GS mouse monoclonal antibody, clone OTI2C12
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI2C12 |
Applications | IHC |
Recommended Dilution | IHC 1:700 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human GS (NP_001028228) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 42.1 kDa |
Gene Name | glutamate-ammonia ligase |
Database Link | |
Background | The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
Synonyms | GLNS; GS; PIG43; PIG59 |
Reference Data | |
Protein Pathways | Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways, Nitrogen metabolism |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA814202 | GS mouse monoclonal antibody, clone OTI2C12 |
USD 447.00 |
|
TA814202AM | GS mouse monoclonal antibody, clone OTI2C12, Biotinylated |
USD 509.00 |
|
TA814202BM | GS mouse monoclonal antibody, clone OTI2C12, HRP conjugated |
USD 509.00 |
|
TA814202S | GS mouse monoclonal antibody, clone OTI2C12 |
USD 200.00 |
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