Botulinum neurotoxin type A Rabbit Polyclonal Antibody

CAT#: BP2271

Botulinum neurotoxin type A rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: ELISA (1/10,000).
  Dot blot.
  Western blot.
• Reactivities: Clostridium botulinum
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Type A Neurotoxin and Complexing Proteins Toxoid.
• Specificity: Recognizes C. Botulinum Type A Neurotoxin Complex, neurotoxin or protein isolates.
• Formulation: 1x PBS, pH 7.2 containing 20% Glycerol
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: None
• Concentration: lot specific
• Purification: Protein G Sepharose Chromatography
• Conjugation: Unconjugated
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  UniProt ID P10845
• Background: Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.
• Synonyms: BoNT/A, Clostridium botulinum Toxin A, Bontoxilysin-A, BOTOX