Progesterone Rabbit Polyclonal Antibody
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | Immunohistochemistry on Frozen Sections: 1/50. Immunohistochemistry on Paraffin Sections: 1/50 Positive Control Tissue: Breast carcinoma and normal young ovarian tissue. Progesterone antibody requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. |
Reactivities | var. |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Progesterone conjugated to BSA |
Specificity | This antibody is specific for Progesterone. In normal tissues it stains granulosa cells and theca cells. It can also be used to stain tumourous Sertoli-Leydig, granulosa and theca cells. |
Formulation | PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein G |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Background | Progesteron is a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland. Progesterone is secreted by the corpus luteum and acts to prepare the endometrium for the implantation of a fertilized egg. During pregnancy, it is secreted by the placenta in order to prevent spontaneous abortion and to stimulate the development of mammary tissue to produce milk. Progesterone is available as a pharmaceutical that can be used to treat menstrual disorders and for the prevention of miscarriage. |
Synonyms | 20-dione, pregn-4-ene-3 |
Reference Data |
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