Candida albicans Rabbit Polyclonal Antibody
Candida albicans rabbit polyclonal antibody, Purified
Product Datasheet for 'BP1006'
|Applications||ELISA, ID, Ie, IF, IHC|
CIE (Counter Immunoelectrophoresis).
Also suitable for Conjugation purposes.
Use neat in gel-precipitin reactions.
|Immunogen||Candida albicans, type A (ATTCC #32354).|
|Specificity||Recognizes numerous proteins in a soluble C. albicans extract (IEP).
Has not been absorbed and does cross-react with other Yeasts.
Negative against Human serum, urine and spinal fluid.
|Formulation||0.01M PBS, pH 7.2 containing 0.09% Sodium Azide as preservative without stabilizing proteins
State: Liquid purified Ig fraction (>95% pure)
|Concentration||4-5 mg/ml (OD280 nm, E0.1% = 1.4)|
|Purification||Protein A Chromatography|
|Background||Candida albicans is the most frequently isolated fungal pathogen of Humans, affecting immunocompromised patients ranging from premature infants to AIDS sufferers. Systemic infections have an attributed mortality of 30-50%. C. albicans is a diploid organism which has eight sets of homologous chromosomes. It has a genome of approximately 16 Mb (haploid), about 30% greater than S. cerevisiae (baker's yeast).|
|The use of this Antibodies has been cited in the following citations:|
Keeping Candida commensal - How lactobacilli antagonize pathogenicity of Candida albicans in an in vitro gut model
,Graf, K;Last, A;Gratz, R;Allert, S;Linde, S;Westermann, M;Gröger, M;Mosig, AS;Gresnigt, MS;Hube, B;,
Dis Model Mech 2019
,PubMed ID 31413153
Proteolytic cleavage of covalently linked cell wall proteins by Candida albicans Sap9 and Sap10.
,Schild L, Heyken A, de Groot PW, Hiller E, Mock M, de Koster C, Horn U, Rupp S, Hube B,
Eukaryotic Cell 2018
,PubMed ID 21097664
Binding of Candida albicans to Human CEACAM1 and CEACAM6 Modulates the Inflammatory Response of Intestinal Epithelial Cells.
,Klaile E, M|ller MM, Schdfer MR, Clauder AK, Feer S, Heyl KA, Stock M, Klassert TE, Zipfel PF, Singer BB, Slevogt H,
,PubMed ID 28292985
Intestinal Cell Tight Junctions Limit Invasion of Candida albicans through Active Penetration and Endocytosis in the Early Stages of the Interaction of the Fungus with the Intestinal Barrier.
,Goyer M, Loiselet A, Bon F, L'Ollivier C, Laue M, Holland G, Bonnin A, Dalle F,
PLoS ONE 2018
,PubMed ID 26933885
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