Cd68 Mouse Monoclonal Antibody [Clone ID: ED1]

SKU BM4000R

Cd68 mouse monoclonal antibody, clone ED1, PE

Product Data

• Clone Name: ED1
• Application: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of Neat-1/10 diluted antibody to label 10⁶ cells in 100 µl.; Results maybe enhanced using membrane permeabilisation.
• Reactivity: Bovine, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Rat spleen cells. ; Spleen cells from immunised BALB/c mice were fused with cells of the SP2/0-Ag14 mouse myeloma cell line.
• Specificity: This antibody recognises CD68.
• Buffer: PBS; Label: PE; State: Lyophilized purified IgG fraction.; Stabilizer: 1% BSA; Preservative: 0.09% Sodium Azide; Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Restore with 1 ml distilled water
• Purification: Affinity Chromatography on Protein A
• Conjugation: PE
• Storage: Prior to and following reconstitution store the antibody at 2-8°C.; DO NOT FREEZE!; This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Gene Name: Cd68 molecule
• Database Link:
  Q4FZY1
• Background: The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
• Synonyms: Gp110, Macrosialin, Macrophage marker

Reference Data