Mouse Monoclonal Antibody [Clone ID: 1-M-12]

CAT#: BM3261

mouse monoclonal antibody, clone 1-M-12, Purified

Specifications

Product Data

• Clone Name: 1-M-12
• Applications: ELISA, IF, WB
• Recommended Dilution: ELISA (1/10,000).
  Western blot (1/1,000).
  Immunofluorescence (1/1,000).
• Reactivities: Cytomegalovirus
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: HCMV infected cell.
• Specificity: Detects Cytomegalovirus Glycoprotein B antigen.
• Formulation: 1xPBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: 0.01% Sodium Azide
• Concentration: lot specific
• Purification: Protein A Sepharose Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  UniProt ID P06473
• Background: Human Cytomegalovirus (HCMV) glycoprotein B (gB) is an abundant virion envelope protein that has been shown to be essential for the infectivity of HCMV. HCMV gB is also one of the most immunogenic virus-encoded proteins, and a significant fraction of virus neutralizing antibodies are directed at gB.
  Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for CMV mediated membrane fusion along with the gH/gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, wit a MW of approximately 100 kDa.
  Cytomegalovirus is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella zoster virus (which causes chicken pox), and Epstein Barr virus (which causes infectious mononucleosis). These viruses share a characteristic ability to remain dormant within the body over a long period.
• Synonyms: HCMV, HHV5, Glycoprotein B, UL55, Cytomegalovirus