CD56 Mouse Monoclonal Antibody [Clone ID: MEM-188]

CAT#: BM2401PP

CD56 mouse monoclonal antibody, clone MEM-188, PerCP

Product Images

Surface staining of human peripheral blood cells with anti-CD56 FITC (BM2401F).

Specifications

Product Data

• Clone Name: MEM-188
• Applications: FC
• Recommended Dilution: Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension.
  The content of a vial (1 ml) is sufficient for 100 tests.
• Reactivities: Human, Primate
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: KG-1 human acute myelogenous leukemia cell line
• Specificity: This antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
• Formulation: Phosphate buffered saline (PBS)
  Label: PerCP
  State: Liquid purified Ig fraction
  Preservative: 15 mM sodium azide
• Conjugation: PerCP
• Storage: Store undiluted at 2-8°C. DO NOT FREEZE! This products is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: neural cell adhesion molecule 1
• Database Link:
  Entrez Gene 4684 Human
  UniProt ID P13591
• Background: CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.
• Synonyms: NCAM-1, N-CAM-1, NCAM

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Prion diseases