CD56 (NCAM1) Mouse Monoclonal Antibody [Clone ID: MEM-188]

CAT#: BM2401F

CD56 (NCAM1) mouse monoclonal antibody, clone MEM-188, FITC

Product Images

Surface staining of human peripheral blood cells with anti-CD56 (MEM-188) FITC.

Specifications

Product Data

• Clone Name: MEM-188
• Applications: FC
• Recommended Dilution: Flow cytometry: use 20 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension.
• Reactivities: Human, Primate
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: KG-1 human acute myelogenous leukaemia cell line
• Specificity: The antibody reacts with a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
• Formulation: Phosphate buffered saline (PBS) containing 15 mM sodium azide
  Label: FITC
  State: Liquid purified Ig fraction
  Label: Conjugated with Fluorescein isothiocyanate under optimum conditions. The reagent is free of unconjugated and adjusted for direct use.
• Conjugation: FITC
• Storage: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: neural cell adhesion molecule 1
• Database Link:
  Entrez Gene 4684 Human
  UniProt ID P13591
• Background: CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours.
• Synonyms: NCAM-1, N-CAM-1, NCAM