Haemophilus influenzae Type B Mouse Monoclonal Antibody [Clone ID: 1079/457]

CAT#: BM1122

Haemophilus influenzae Type B mouse monoclonal antibody, clone 1079/457, Purified

Specifications

Product Data

• Clone Name: 1079/457
• Applications: ELISA, IF
• Recommended Dilution: ELISA.
  Immunofluorescence.
• Reactivities: Haemophilus influenzae
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Haemophilus influenzae B, NCTC 7279
• Specificity: This antibody recognizes Haemophilus influenzae B, a gram-negative coccobacillus that is the cause of bacterial meningitis and other severe illnesses in young children.
  In a simple ELISA this antibody (previous lots) is not reactive with the following: Neisseria meningitidis groups A (NCTC 10025), B (NCTC 10026), C (NCTC 8554) and D (NCTC 9714), Acinetobacter calcoaceticus (NCTC 7844), Branhamella catarrhalis (NCTC 11020), Gamella haemolysans (NCTC 10243), Moraxella nonliquefaciens (NCTC 10464), Moraxella phenylpyruvica (NCTC 10526), Veillonella parvula (NCTC 11463), various types of E.coli, various species of Neisseria, Salmonella.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Aaffinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background: Haemophilus influenzae is a small, nonmotile Gram negative bacterium found naturally in the nasopharynx of approximately 75 percent of healthy children and adults. The presence of the type B polysaccharide capsule is the major factor in virulence. Encapsulated organisms can penetrate the epithelium of the nasopharynx and invade the blood capillaries directly. Their capsule allows them to resist phagocytosis and complement mediated lysis in the the nonimmune host and cause bacteremia and acute bacterial meningitis in infants and young children. Occasionally epiglottitis cellulitis, osteomyelitis, and joint infections can be caused.