Mouse Monoclonal Antibody [Clone ID: HCMV37]

CAT#: BM1057

mouse monoclonal antibody, clone HCMV37, Purified

Specifications

Product Data

• Clone Name: HCMV37
• Applications: ELISA, IF, IHC, Neutralize
• Recommended Dilution: ELISA.
  Immunofluorescence: Reactive only in acetone fixed CMV infected cells or frozen sections.
• Reactivities: Cytomegalovirus
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human CMV extracts.
• Specificity: The antibody is specific for Cytomegalovirus glycoprotein B late neutralizing antigen.
  Reacts with MRC-5 infected cells but not uninfected cells.
  This antibody has been found to be Neutralizing.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  UniProt ID P06473
• Background: Human Cytomegalovirus (HCMV) glycoprotein B (gB) is an abundant virion envelope protein that has been shown to be essential for the infectivity of HCMV. HCMV gB is also one of the most immunogenic virus-encoded proteins, and a significant fraction of virus neutralizing antibodies are directed at gB.
  Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for CMV mediated membrane fusion along with the gH/gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, wit a MW of approximately 100 kDa.
• Synonyms: HCMV, HHV5, Glycoprotein B, UL55, Cytomegalovirus