Integrin Linked Kinase (ILK) pSer246 Rabbit Polyclonal Antibody
CAT#: AP55757PU-N
Integrin Linked Kinase (ILK) pSer246 rabbit polyclonal antibody, Aff - Purified
Size: 50 ul
Other products for "ILK"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | Immunohistochemistry on paraffin sections: 1:50~1:100 . |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide sequence around phosphorylation site of Serine 246(I-F-S(p)-H-P) derived from Human ILK (KLH-conjugated) |
Specificity | The antibody detects endogenous levels of ILK only when phosphorylated at serine 246. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography using epitope-specific peptide |
Conjugation | Unconjugated |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 51 kDa |
Gene Name | integrin linked kinase |
Database Link | |
Background | Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. |
Synonyms | ILK-1, ILK-2, p59ILK, ILK, ILK1, ILK2 |
Reference Data |
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