VEGF Receptor 2 (KDR) Rabbit Polyclonal Antibody
Other products for "VEGF Receptor 2"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1:1;000. Western blot: 1:50~100. Immunohistochemistry on paraffin sections: 1:50~100. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Specificity | This antibody detects CD309 / VEGFR-2 / Flk-1. |
Formulation | PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
Conjugation | Unconjugated |
Storage | Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | kinase insert domain receptor |
Database Link | |
Background | VEGF is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. |
Synonyms | VEGFR2, FLK1, KDR, VEGF Receptor 2 |
Note | Molecular Weight: 149256 Da |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, VEGF signaling pathway |
Documents
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