UGT2B15 (Center) Rabbit Polyclonal Antibody

CAT#: AP54455PU-N

UGT2B15 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

UGT2B15 Antibody (Center) western blot analysis in NCI-H460, HepG2, ZR-75-1 cell line lysates (35 ug/lane). This demonstrates the UGT2B15 antibody detected the UGT2B15 protein (arrow).

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  UGT2B15 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of UGT2B15 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

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  Confocal immunofluorescent analysis of UGT2B15 Antibody (Center) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ELISA: 1:1;000
  Western blot: 1:100~500.
  Immunohistochemistry on paraffin sections: 1:10~50.
  Immunofluorescence: 1:10~50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 163-193 amino acids from the Central region of human UGT2B15
• Specificity: This antibody detects UGT2B15 / UGT2B8 (Center).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: UDP glucuronosyltransferase family 2 member B15
• Database Link:
  Entrez Gene 7366 Human
  UniProt ID P54855
• Background: The UGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B8 demonstrates reactivity with estriol. See UGT2B4 (MIM 600067).
• Synonyms: UDP-glucuronosyltransferase 2B15, UDPGT 2B15, UDPGTh-3, HLUG4
• Note: Molecular Weight: 60988 Da

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Androgen and estrogen metabolism, Ascorbate and aldarate metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pentose and glucuronate interconversions, Porphyrin and chlorophyll metabolism, Retinol metabolism, Starch and sucrose metabolism