TGFBI (N-term) Rabbit Polyclonal Antibody

CAT#: AP54232PU-N

TGFBI (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of TGFBI (arrow) using rabbit polyclonal TGFBI Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TGFBI gene.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1;000.
  Western blot: 1:100~500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 105-135 amino acids from the N-terminal region of human TGFBI
• Specificity: Thisa ntibody detects TGFBI / BIGH3 (N-term).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: transforming growth factor beta induced
• Database Link:
  Entrez Gene 7045 Human
  UniProt ID Q15582
• Background: This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
• Synonyms: Beta ig-h3, RGD-CAP, Kerato-epithelin
• Note: Molecular Weight: 74681 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane