OATP2 (SLCO1B1) (Center) Rabbit Polyclonal Antibody

CAT#: AP53929PU-N

OATP2 (SLCO1B1) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of SLCO1B1 / OATP2 Antibody (Center) in HepG2 cell line lysates (35ug/lane). SLCO1B1 (arrow) was detected using the purified Pab

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 273~302 amino acids from the Central region of Human SLCO1B1
• Specificity: This antibody recognizes Human SLCO1B1 (Center).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: solute carrier organic anion transporter family member 1B1
• Database Link:
  Entrez Gene 10599 Human
  UniProt ID Q9Y6L6
• Background:
  SLCO1B1 is a liver-specific member of the organic anion transporter family. This protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
  
  
• Synonyms: LST1, LST-1, OATP-2, OATPC, OATP-C, SLC21A6
• Note: Molecular Weight: 76449 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane