KAT2B (C-term) Rabbit Polyclonal Antibody

CAT#: AP53187PU-N

KAT2B (C-term) rabbit polyclonal antibody, Purified

Product Images

PCAF Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the PCAF antibody detected the PCAF protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 802-832 amino acids from the C-terminal region of human PCAF
• Specificity: This antibody reacts to PCAF.
• Formulation: PBS
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 93013 Da
• Gene Name: lysine acetyltransferase 2B
• Database Link:
  Entrez Gene 8850 Human
  UniProt ID Q92831
• Background: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
• Synonyms: Histone acetylase PCAF, P/CAF

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Notch signaling pathway