NEU4 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52856PU-N

NEU4 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of NEU4 Antibody (C-term) in mouse liver tissue lysates (35ug/lane). This demonstrates the NEU4 antibody detected the NEU4 protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma reacted with NEU4 Antibody (C-term), which was peroxidase conjugated to the secondary antibody and followed by DAB staining. This data demonstrates the use of the NEU4 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 430-461 amino acids from the C-terminal region of Human Sialidase-4
• Specificity: This antibody recognizes Human and Mouse Sialidase-4 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: neuraminidase 4 (sialidase)
• Database Link:
  Entrez Gene 241159 MouseEntrez Gene 129807 Human
  UniProt ID Q8WWR8
• Background: The protein encoded by this gene belongs to a family of glycohydrolytic enzymes, which remove terminal sialic acid residues from various sialo derivatives, such as glycoproteins, glycolipids, oligosaccharides, and gangliosides. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Synonyms: NEU4, LP5125, N-acetyl-alpha-neuraminidase 4
• Note: Molecular Weight: 51572 Da

Reference Data

• Protein Pathways: Other glycan degradation, Sphingolipid metabolism