MAML1 (Center) Rabbit Polyclonal Antibody

CAT#: AP52591PU-N

MAML1 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Mastermind-Like Protein 1 Antibody (Center) in 293, NCI-H460 cell line lysates (35ug/lane).

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  Flow cytometric analysis of NCI-H460 cells using Mastermind-Like Protein 1 Antibody (Center) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human Mastermind-Like Protein 1
• Specificity: This antibody recognizes Human Mastermind-Like Protein 1 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: mastermind like transcriptional coactivator 1
• Database Link:
  Entrez Gene 9794 Human
  UniProt ID Q92585
• Background: This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
• Synonyms: MAML1, Mam-1
• Note: Molecular Weight: 108054 Da

Reference Data

• Protein Pathways: Notch signaling pathway