Jagged1 (JAG1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP52261PU-N

Jagged1 (JAG1) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CD339 / JAG1 Antibody (C-term) in K562 cell line lysates (35ug/lane).

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  Flow cytometric analysis of K562 cells using CD339 / JAG1 Antibody (C-term) (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: FC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Flow Cytometry: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 1129-1158 amino acids from the C-terminal region of Human CD339 / JAG1
• Specificity: This antibody recognizes Human CD339 / JAG1 (C-term)
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: jagged 1
• Database Link:
  Entrez Gene 182 Human
  UniProt ID P78504
• Background: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
• Synonyms: Jagged-1, hJ1, JAGL1
• Note: Molecular Weight: 133799 Da

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Notch signaling pathway