IFNGR1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52156PU-N

IFNGR1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

IFNGR1 Antibody (C-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the IFNGR1 antibody detected the IFNGR1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 460-489 amino acids from the C-terminal region of human IFNGR1
• Specificity: This antibody reacts to IFNGR1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 54405 Da
• Gene Name: interferon gamma receptor 1
• Database Link:
  Entrez Gene 3459 Human
  UniProt ID P15260
• Background: This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq].
• Synonyms: Interferon-gamma receptor alpha chain, IFN-gamma-R1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity