HNRNPC (C-term) Rabbit Polyclonal Antibody

CAT#: AP52068PU-N

HNRNPC (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of HNRNPC Antibody (C-term) in Jurkat, K562, U251 cell line lysates (35ug/lane). This demonstrates the HNRNPC antibody detected the HNRNPC protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma reacted with HNRNPC Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 282-310 amino acids from the C-terminal region of human hnRNP-C1/C2 / HNRNPC
• Specificity: This antibody recognizes Human hnRNP-C1/C2 / HNRNPC (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: heterogeneous nuclear ribonucleoprotein C (C1/C2)
• Database Link:
  Entrez Gene 3183 Human
  UniProt ID P07910
• Background: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq].
• Synonyms: Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1 / hnRNP C2, HNRPC
• Note: Molecular Weight: 33670 Da

Reference Data

• Protein Pathways: Spliceosome