HNF 4 alpha (HNF4A) (N-term) Rabbit Polyclonal Antibody

CAT#: AP52067PU-N

HNF 4 alpha (HNF4A) (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of HNF4 alpha / TCF14 Antibody (N-term) in 293 cell line lysates (35ug/lane). HNF4A (arrow) was detected using the purified Pab.

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  Confocal immunofluorescent analysis ofHNF4 alpha / TCF14 Antibody (N-term) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500
  Immunofluorescence: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 116~145 amino acids from the N-terminal region of human HNF4 alpha / TCF14
• Specificity: This antibody recognizes Human HNF4 alpha / TCF14 (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: hepatocyte nuclear factor 4 alpha
• Database Link:
  Entrez Gene 3172 Human
  UniProt ID P41235
• Background: HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines.
• Synonyms: HNF4A, HNF4, NR2A1, Hepatocyte nuclear factor 4-alpha, Transcription factor HNF-4, Transcription factor 14
• Note: Molecular Weight: 52785 Da

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Maturity onset diabetes of the young