DPH4 (DNAJC24) (Center) Rabbit Polyclonal Antibody

CAT#: AP51294PU-N

DPH4 (DNAJC24) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of DPH4Antibody in HL-60 cell line lysates (35ug/lane). This demonstrates the DNAJC24 antibody detected the DNAJC24 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of Human DPH4
• Specificity: This antibody recognizes Human DPH4 (Center).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: DnaJ heat shock protein family (Hsp40) member C24
• Database Link:
  Entrez Gene 120526 Human
  UniProt ID Q6P3W2
• Background: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]). [supplied by OMIM].
• Synonyms: DNAJC24, ZCSL3
• Note: Molecular Weight: 17008 Da