GM CSF (CSF2) (Center) Rabbit Polyclonal Antibody
Other products for "GM CSF"
Specifications
Product Data | |
Applications | FC, IF, IHC, WB |
Recommended Dilution | ELISA: 1/1000. Western blot: 1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/100. Flow Cytometry: 1/10-1/50. Immunofluorescence: 1/10 1/50. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 59-85 amino acids from the Central region of Human CSF2 |
Specificity | This antibody reacts to human CSF2. |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide |
Concentration | lot specific |
Purification | Protein A Chromatography, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 16295 Da |
Gene Name | colony stimulating factor 2 |
Database Link | |
Background | CSF2 is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. [provided by RefSeq]. |
Synonyms | CSF2, GMCSF, Sargramostim, Molgramostin |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein |
Protein Pathways | Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway |
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