CLEC18A (C-term) Rabbit Polyclonal Antibody

CAT#: AP50959PU-N

CLEC18A (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in NCI-H292 cell line lysates (35ug/lane) using CLEC18A Antibody (C-term). This demonstrates the CLEC18A antibody detected the CLEC18A protein (arrow).

• 

  Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue using CLEC18A Antibody (C-term). followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CLEC18A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of Human CLEC18A
• Specificity: This antibody detects CLEC18A at C-term.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 49602 Da
• Gene Name: C-type lectin domain family 18 member A
• Database Link:
  Entrez Gene 348174 Human
  UniProt ID A5D8T8
• Background: The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-18 (C-type lectin domain family 18) exists as three nearly identical forms, designated CLEC-18A, CLEC-18B and CLEC-18C, or mannose receptor-like protein 1, 2 and 3, respectively. Both CLEC-18A and CLEC-18C contain 446 amino acids, whereas CLEC-18B contains 455 amino acids; all three forms are secreted proteins that contain one C-type lectin domain, a SCP domain and a single EGF-like domain. All three CLEC-18 proteins exist as two alternatively spliced isoforms that are encoded by genes that map to human chromosome 16q22.
• Synonyms: MRLP2