Claudin 23 (CLDN23) (C-term) Rabbit Polyclonal Antibody

CAT#: AP50948PU-N

Claudin 23 (CLDN23) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CLDN23 Antibody (C-term) in mouse bladder tissue lysates (35ug/lane). CLDN23 (arrow) was detected using the purified Pab.

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  CLDN23 Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CLDN23 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
  Immunohistochemistry on paraffin sections: 1/50 - 1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 235~265 amino acids from the C-terminal region of human CLDN23
• Specificity: This antibody reacts to CLDN23.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 31915 Da
• Gene Name: claudin 23
• Database Link:
  Entrez Gene 71908 MouseEntrez Gene 137075 Human
  UniProt ID Q96B33
• Background: CLDN23 is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C. It is a candidate tumor suppressor gene implicated in intestinal-type gastric cancer.
• Synonyms: 2310014B08Rik; CLDNL; hCG1646163

Reference Data

• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction