VCAM1 (Center) Rabbit Polyclonal Antibody

CAT#: AP50835PU-N

VCAM1 (Center) rabbit polyclonal antibody, Purified

Product Images

CD106 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CD106 antibody detected the CD106 protein (arrow).

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  CD106 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the CD106 antibody detected the CD106 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/50 - 1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 294-322 amino acids from the Central region of human CD106
• Specificity: This antibody reacts to CD106.
• Formulation: PBS
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 81276 Da
• Gene Name: vascular cell adhesion molecule 1
• Database Link:
  Entrez Gene 22329 MouseEntrez Gene 7412 Human
  UniProt ID P19320
• Background: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
• Synonyms: V-CAM 1, INCAM-100, L1CAM, VCAM-1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration