HERC4 (N-term) Rabbit Polyclonal Antibody

CAT#: AP46011PU-N

HERC4 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Human Liver; WB Suggested Anti-HERC4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Liver; HERC4 antibody - N-terminal region (AP46011PU-N) in Human Liver cells using Western Blot

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  Western blotting (0.2 - 1 µg/ml).

• Reactivities: Bovine, Canine, Human, Mouse, Rat, African clawed frog
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to the N terminal region of human HERC4, Isoform 5
• Formulation: State: Aff - Purified
  State: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Immunoaffinity column
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: HERC4: 13 kDa
• Gene Name: HECT and RLD domain containing E3 ubiquitin protein ligase 4
• Database Link:
  Entrez Gene 26091 Human
  UniProt ID Q5GLZ8
• Background: HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.
• Synonyms: KIAA1593