Annexin A3 (ANXA3) Rabbit Polyclonal Antibody

CAT#: AP31912PU-N

Annexin A3 (ANXA3) rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution:

  ELISA.
  Western Blot: 1/500-1/5000.
  Immunohistochemistry: 1/200-1/5000.

• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from internal part of Human Annexin A3.
• Specificity: Reacts with Human Annexin A3 .
  May cross react with protein from Primates due to sequence homology.
• Formulation: 0.1M Tris, 0.1M Glycine, 2% Sucrose
  State: Purified
  State: Lyophilized powder
  Preservative: None
• Reconstitution Method: Restore in distilled water
• Purification: Protein A Chromatography
• Conjugation: Unconjugated
• Storage:

  Lyophilized powder stable for a minimum of 2 years at -20°C.
  Store reconstituted antibody at 2-4°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: Six months from despatch.

• Gene Name: annexin A3
• Database Link:
  Entrez Gene 306 Human
  UniProt ID P12429
• Background: The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain, which binds phospholipids in a Ca2⁺-dependent manner, and a unique amino-terminal region, which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis, exocytosis and cellular adhesion. Annexin III, also known as ANXA3, Annexin A3, Lipocortin III, PAP-III (placental anticoagulant protein III), 35-α calcimedin or ANX3, belongs to the Annexin family and contains four Annexin repeats. Annexin III exhibits a variety of functions, including anti-coagulent properties, an inhibitory role towards phospholipase A2 (PLA2) and an enzymatic function, cleaving the cyclic bond of inositol 1,2-cyclic phosphate to produce inositol 1-phosphate.
• Synonyms: ANX3, Annexin-3, Annexin III, PAP-III, Lipocortin III, 35-alpha calcimedin