KCNK2 (4-14) Rabbit Polyclonal Antibody

CAT#: AP26423AF-N

KCNK2 (4-14) rabbit polyclonal antibody, Azide Free

Product Images

Western blot analysis of Jurkat cell extract using rabbit anti-trek1.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: ELISA: The antibody (1:500,000 diluted) can detect the TREK-1 peptide coated on ELISA plate at 100ng/well.
  Western blot: Dilute approx. 1:3,000 to detect the 47kDa TREK-1 in Jurkat cell extract.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: A synthetic peptide derived from the amino sequence 4-14 of human TREK-1, conjugated with KLH
• Specificity: This antibody reacts with the 47kDa TREK-1 in Jurkat cell extract.
• Formulation: 0.01M PBS, pH 7.4
  State: Azide Free
  State: Lyophilized Ig fraction
• Reconstitution Method: Restore with double distilled water to adjust the final concentration to 1.00 mg/ml.
• Purification: Protein G affinity
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 month or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: potassium two pore domain channel subfamily K member 2
• Database Link:
  Entrez Gene 3776 Human
  UniProt ID O95069
• Background: TWIK-related potassium channel 1(TREK-1), also known as K2P2.1, is a two pore domain gated potassium channel that is involved with pain reception. TREK-1 is highly expressed in small sensory neurons and is extensively colocalized with TRPV1. TREK-1 is sensitive to noxious stimuli including extracellular pH, temperature, mechanical force, osmotic pressure and other stimuli. TREK-1 is one of the targets for pain mediator and anaesthesia drug.
• Synonyms: KCNK2, TREK, TREK1, Potassium channel subfamily K member 2, Two pore potassium channel TPKC1