LY75 (LY75-CD302) Chicken Polyclonal Antibody

CAT#: AP26335PU-N

LY75 (LY75-CD302) chicken polyclonal antibody, Aff - Purified

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on frozen sections: 2-5μg/ml (1:80 - 1:200).
  Immunohistochemistry on paraffin sections: 2-5μg/ml (1:80-1:200).
  Proteinase K pretreatment for antigen retrieval is recommended.
  Suggested positive control: Human tonsil or skin sections.
• Reactivities: Human
• Host: Chicken
• Clonality: Polyclonal
• Immunogen: Synthetic peptide coupled to carreir protein.
  The antibody was made against a central part of the Ricin B-type lectin, a domain located in the N-terminal extracellular portion of the DEC-205 protein.
• Specificity: This antibody detects CD205.
• Formulation: Stock solution contains 0.4mg/ml IgY, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA) as a stabilizer and 0.01% Kathon as a preservative.
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: Reconstitute by adding 0.5ml distilled water.
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: LY75-CD302 readthrough
• Database Link:
  Entrez Gene 100526664 Human
  UniProt ID O60449
• Background: Type I cell surface protein is expressed primarily by dendritic cells (DC). It is found on interdigitating dendritic cells in T-cell areas of lymphoid tissues, bone marrow-derived DC, Langerhans cells and at low levels on macrophages and T-cells. Tissue distribution of DEC-205 is comparable between human and mouse.
• Synonyms: LY75, CLEC13B, DEC205, gp200-MR6