Foxp3 (C-term) Goat Polyclonal Antibody
Other products for "Foxp3"
Specifications
Product Data | |
Applications | ELISA, IHC |
Recommended Dilution | Peptide ELISA: 1/4000. Immunohistochemistry: 2-4 µg/ml. In paraffin embedded Mouse Thymus shows nuclear staining in some patches of thymocytes. |
Reactivities | Mouse, Rat |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Peptide with sequence from the C Terminus of the protein sequence according to NP_473380.1. |
Specificity | Recognizes FOXP3 / Scurfin (Mouse). |
Formulation | Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer. State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide. |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | forkhead box P3 |
Database Link | |
Background | FOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells. |
Synonyms | Forkhead box protein P3, IPEX, JM2, Scurfin |
Reference Data |
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