TLR3 (514-657) Rabbit Polyclonal Antibody

CAT#: AP23628PU-N

TLR3 (514-657) rabbit polyclonal antibody, Aff - Purified

Product Images

Sample (30 ug of whole cell lysate). A: Molt-4. 7.5% SDS PAGE. TLR3 antibody diluted at 1/5000.

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  Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence analysis of methanol-fixed HeLa, using TLR3 antibody at 1/200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunocytochemistry.
  Immunofluorescence: 1/100 - 1/200.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/1000 - 1/10000.
• Reactivities: Bovine, Feline, Guinea Pig, Human, Monkey, Mouse, Porcine, Rabbit, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: TLR3 antibody was raised against recombinant protein fragment containing a sequence corresponding to a region within amino acids 514 and 657 of TLR3.
• Specificity: This antibody reacts to Toll-like Receptor 3 (TLR3) at aa 514-657.
• Formulation: 0.1 M Tris-glycine, pH 7.0 containing 10% Glycerol and 0.01% Thimerosal
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: toll like receptor 3
• Database Link:
  Entrez Gene 142980 MouseEntrez Gene 364594 RatEntrez Gene 7098 Human
  UniProt ID O15455
• Background: TLR3 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.
• Synonyms: Toll-like receptor 3

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Toll-like receptor signaling pathway