FGF1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP23402PU-N

FGF1 (C-term) rabbit polyclonal antibody, Aff - Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1 μg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human FGF1
• Specificity: This antibody detects FGF acidic / FGF1 (C-term). No cross reactivity with other proteins.
• Formulation: 0.2ml of distilled water will yield a concentration of 500μg/ml.
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: PA1311
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: fibroblast growth factor 1
• Database Link:
  Entrez Gene 14164 MouseEntrez Gene 25317 RatEntrez Gene 2246 Human
  UniProt ID P05230
• Background: Fibroblast growth factor 1 (acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q311. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm-and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Additionally, Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. Alpha-ECGF is also derived from ECGFB in the same manner.
• Synonyms: FGFA, Acidic fibroblast growth factor, ECGF-beta, HBGF-1, HBGF1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton