Claudin 1 (CLDN1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP22702PU-N

Claudin 1 (CLDN1) (C-term) rabbit polyclonal antibody, Purified

Product Images

Human Colon (formalin-fixed, paraffin-embedded) stained with CLDN1 antibody AP22702PU-N at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Skin (formalin-fixed, paraffin-embedded) stained with CLDN1 antibody AP22702PU-N at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml
  (After heat induced antigen retrieval in pH 6.0 citrate buffer).
• Reactivities: Canine, Human, Monkey, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: CLDN1 antibody was raised against a synthetic peptide derived from the C-terminus of human Claudin-1
• Specificity: This antibody reacts to Claudin 1 (CLDN1).
• Formulation: 10 mM PBS, pH 7.4, 1% BSA, 0.09% sodium azide
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: claudin 1
• Database Link:
  Entrez Gene 12737 MouseEntrez Gene 65129 RatEntrez Gene 9076 Human
  UniProt ID O95832
• Background: Claudins are integral membrane proteins that constitute tight junctions found in endothelial and epithelial cells to determine vascular permeability
• Synonyms: CLD1, SEMP1, PRO944, UNQ481

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Tight junction