Glutathione Peroxidase 3 (GPX3) (102-114) Goat Polyclonal Antibody

CAT#: AP22523PU-N

Glutathione Peroxidase 3 (GPX3) (102-114) goat polyclonal antibody

Product Images

Antibody (1 ug/ml) staining of Mouse Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  Human Colon (formalin-fixed, paraffin-embedded) stained with GPX3 antibody AP22523PU-N at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Placenta (formalin-fixed, paraffin-embedded) stained with GPX3 antibody AP22523PU-N at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1 - 3 µg/ml.
• Reactivities: Canine, Human, Mouse, Rat, Bovine, Bat, Equine, Monkey, Porcine
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from internal region of human GPX3
• Specificity: This antibody detects Glutathione peroxidase 3 at aa 102-114.
  It may cross-react with epididymis-specific GPX5 and olfactory epithelium-speciific GPX6.
• Formulation: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: glutathione peroxidase 3
• Database Link:
  Entrez Gene 14778 MouseEntrez Gene 64317 RatEntrez Gene 2878 Human
  UniProt ID P22352
• Background: Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme. GPX3 expression appears to be tissue-specific.
• Synonyms: GPX-3, GPXP, GSHPx-3, GPx-3, GSHPx-P, GSHPXP, GPx-P, GPXP

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Arachidonic acid metabolism, Glutathione metabolism