FANCG (609-622) Goat Polyclonal Antibody

CAT#: AP22490PU-N

FANCG (609-622) goat polyclonal antibody, Aff - Purified

Product Images

Antibody (0.5 ug/ml) staining of HeLa cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• 

  Human Spleen (formalin-fixed, paraffin-embedded) stained with FANCG antibody at 3 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

• 

  Human Uterus (formalin-fixed, paraffin-embedded) stained with FANCG antibody at 3 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/32000.
  Immunohistochemistry on Paraffin Sections: 3 µg/ml.
  Western Blot: 0.5 - 1 µg/ml.
• Reactivities: Human, Monkey
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from C-term of human FANCG
• Specificity: This antibody detects XRCC9 / FANCG (C-term).
• Formulation: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Fanconi anemia complementation group G
• Database Link:
  Entrez Gene 2189 Human
  UniProt ID O15287
• Background: FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified. The FANCG gene is responsible for complementation group G.
• Synonyms: FACG, Fanconi anemia group G protein

Reference Data

• Protein Families: Druggable Genome