CD69 Rabbit Polyclonal Antibody

CAT#: AP21168PU-N

CD69 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of CD69 antibody (Cat.-No.: AP21168PU-N) in extracts from HUVEC cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500-1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of CD69 protein.
  (region surrounding Arg134)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~23 kDa
• Gene Name: CD69 molecule
• Database Link:
  Entrez Gene 12515 MouseEntrez Gene 29187 RatEntrez Gene 969 Human
  UniProt ID Q07108
• Background: CD69 is a disulfide linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C type lectin, most closely related to the NKRP1 and Ly49 NK cell activation molecules. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. It is the earliest inducible cell surface glycoprotein acquired during lymphoid activation. Induction occurs by antigens, mitogens or activators of PKC on the surface of T and B lymphocytes, and by interaction of IL2 with the p75 IL2R on the surface of NK cells. Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells.
• Synonyms: GP32/28, Leu-23, MLR-3, EA1, BL-AC/P26, AIM

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane