PKC epsilon (PRKCE) Rabbit Polyclonal Antibody

CAT#: AP20353PU-N

PKC epsilon (PRKCE) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PKC e antibody (Cat.-No.: AP20353PU-N) in extracts from HeLa cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500-1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of PKC ε protein.
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 83 kDa
• Gene Name: protein kinase C epsilon
• Database Link:
  Entrez Gene 18754 MouseEntrez Gene 29340 RatEntrez Gene 5581 Human
  UniProt ID Q02156
• Background: Members of the protein kinase C family fall into three categories: conventional (PKC alph,a beta I, beta II, gamma), novel (delt,a epsilon, et,a mu, theta), and atypical (lamd,a zeta). Conventional PKC isoforms are dependent on calcium and diacylglycerol (DAG) for their activity, whereas novel PKC isoforms are calcium dependent, and atypical PKC isoforms are calcium and DAG independent.
• Synonyms: PKC-epsilon, PKC epsilon, PKCE, Protein kinase C epsilon type

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction