Moesin (MSN) Rabbit Polyclonal Antibody

CAT#: AP20258PU-N

Moesin (MSN) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Moesin antibody (Cat.-No.: AP20258PU-N) in extracts from A549 cells.

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  Immunohistochemistry analyzes of Moesin antibody (AP20258PU-N) in paraffin-embedded human pancreas tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Moesin protein.
• Formulation: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: ~ 78 kDa
• Gene Name: moesin
• Database Link:
  Entrez Gene 17698 MouseEntrez Gene 81521 RatEntrez Gene 4478 Human
  UniProt ID P26038
• Background: Moesin is a member of the ERM (Ezrin-Radixin-Moesin) protein family, which possesses structural and probably functional relationships; they function as plasma membrane-actin cytoskeleton linkers and participate in the formation of specialized domains of the plasma membrane and are all localized to the submembranous cytoskeleton. Moesin is widely expressed in different tissues in cells, where it is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signalling and for cell movement. The antibody has been used to inhibit both the binding of proteoheparan sulfate to smooth muscle cells, and the infectivity of measles virus.
• Synonyms: MSN

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Leukocyte transendothelial migration, Regulation of actin cytoskeleton