TMPRSS2 (Center) Rabbit Polyclonal Antibody
TMPRSS2 (Center) rabbit polyclonal antibody
|Recommended Dilution||ELISA: 1/1,000.
Western blotting: 1/50 - 1/100.
|Immunogen||KLH conjugated synthetic peptide selected from the Center region of human TMPRSS2|
|Specificity||This antibody reacts to TMPRSS2.|
|Formulation||PBS with 0.09% (W/V) sodium azide
State: Liquid purified Ig
|Purification||Saturated Ammonium Sulfate (SAS) precipitation|
|Storage||Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
|Stability||Shelf life: one year from despatch.|
|Gene Name||Homo sapiens transmembrane protease, serine 2 (TMPRSS2), transcript variant 2|
|Background||TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.|
|Synonyms||Transmembrane protease serine 2, PRSS10, Serine protease 10|
|Protein Families||Druggable Genome, Protease, Secreted Protein, Transmembrane|