HMGCS2 (C-term) Rabbit Polyclonal Antibody

CAT#: AP17475PU-N

HMGCS2 (C-term) rabbit polyclonal antibody

Product Images

Western blot analysis of HMGCS2 Antibody (C-term) in HepG2 cell line lysates (35ug/lane). HMGCS2 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human HMGCS2
• Specificity: This antibody reacts to HMGCS2.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: 3-hydroxy-3-methylglutaryl-CoA synthase 2
• Database Link:
  Entrez Gene 3158 Human
  UniProt ID P54868
• Background: HMGCS2 belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting.
• Synonyms: mitochondrial HMG-CoA synthase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Butanoate metabolism, Metabolic pathways, PPAR signaling pathway, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Valine, leucine and isoleucine degradation